The Fed meeting, pressure on Oracle, Target’s fashion-forward renovation and more in Morning Squawk

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Television stations broadcast Jerome Powell, chairman of the US Federal Reserve, speaking after a Federal Open Market Committee (FOMC) meeting on the floor of the New York Stock Exchange in New York, US, on Wednesday, Oct. 29, 2025.

Michael Nagle | Bloomberg | Getty Images

This is CNBC’s Morning Squawk newsletter. Subscribe here to receive future editions in your inbox.

Here are five key things investors need to know to start the trading day:

1. Setting expectations

We’re counting down to the Federal Reserve’s interest rate decision this afternoon and Chair Jerome Powell’s subsequent press conference. Despite broad expectations that the central bank will cut rates, traders haven’t been rushing into the stock market ahead of the announcement.

Here’s what to know:

2. Oracle’s omen

The Oracle logo is displayed on a building at an Oracle campus on Sept. 10, 2025 in Redwood Shores, California.

Justin Sullivan | Getty Images

After Powell finishes his conference, investors won’t have long to wait before another potential market catalyst. Oracle is reporting its second quarter earnings after the bell — and the pressure is on.

As CNBC’s Seema Mody notes, the technology company needs to show it can continue to finance its bold infrastructure plans. Oracle has emerged as a leader within artificial intelligence in recent months, so the company also needs to prove its AI-driven growth story is sound.

Oracle shares are little changed in premarket trading this morning. The stock is up more than 30% this year, even after seeing its biggest one-month drop in more than two decades in October.

3. Pharma’s shopping cart

Eli Lilly’s new planned manufacturing facility in Huntsville, Alabama.

Courtesy: Eli Lilly

Big pharma is cutting big checks as it bets on obesity pills.

Eli Lilly said yesterday it would spend $6 billion building a manufacturing plant in Huntsville, Alabama, to support the production of its experimental obesity pill, along with other drugs. As CNBC’s Annika Kim Constantino notes, it’s the third facility the company has announced as part of its plan to increase domestic manufacturing.

Pfizer, meanwhile, announced a $2.1 billion licensing deal with Chinese-owned YaoPharma to develop and commercialize its obesity pill. The agreement marks Pfizer’s latest push into the blockbuster weight-loss market following its acquisition of Metsera last month.

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4. Un-pausing payments

Students walk on campus at Harvard University, in Cambridge, Massachusetts, U.S., Nov. 19, 2025.

Reba Saldanha | Reuters

Millions of student loan borrowers whose payments have been on pause could soon be forced to restart payments. The Department of Education said yesterday that a proposed settlement would require borrowers enrolled in the Biden-era Saving on a Valuable Education, or SAVE, plan to select a new repayment method.

The proposal comes as new data shows 42% of student loan borrowers said they have a harder time paying for necessities such as food and housing as a result of their monthly payments. More than half of respondents said their debt has made it more difficult to save for retirement.

5. Target, or Tarzhay?

Target has turned its store in New York City’s SoHo neighborhood into a unique concept store. Inside of an area that resembles the company’s Bullseye logo, the company has “The Drop,” a rotating display of seasonal styles and curated items.

Courtesy of Target

Target is trying to position itself as a trend and style leader. It’s doing so in one of New York City’s most fashionable neighborhoods.

The retailer has renovated its SoHo store to include rotating merchandise, a beauty bar and displays curated by celebrities and influencers. Incoming CEO Michael Fiddelke called the location “a punctuation point” for Target’s style sensibilities and its future path as the company aims to win back consumers’ discretionary dollars.

As CNBC’s Melissa Repko reports, the redesign of the store’s first floor took four months, with Target rushing to reopen the location in time for the holiday season. Click here to take a look inside.

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CNBC’s Jeff Cox, Sean Conlon, Hugh Son, Steve Liesman, John Melloy, Seema Mody, Annika Kim Constantino, Annie Nova and Melissa Repko contributed to this report. Josephine Rozzelle edited this edition.